Yes, certain drugs can cause seizures as a side effect or during withdrawal. Drugs that have a direct effect on the brain and nervous system, such as stimulants (e.g. cocaine, amphetamines), depressants (e.g. benzodiazepines, alcohol), and opioids (e.g. heroin, fentanyl), are known to increase the risk of seizures. Additionally, abruptly stopping or reducing the dosage of certain medications can also trigger seizures as part of a withdrawal syndrome. It is important to always take medication as prescribed by a healthcare provider and to seek medical attention immediately if experiencing seizures or other symptoms.