Yes, taking too much Ambien (zolpidem) can be fatal. Ambien is a sedative-hypnotic medication used for the short-term treatment of insomnia. If taken in larger doses than prescribed or taken with other substances that enhance the effects of Ambien, it can lead to overdose and even death. Signs of an Ambien overdose may include excessive drowsiness, confusion, slowed or difficulty breathing, and unconsciousness. It is important to always take Ambien as prescribed by a healthcare provider and never exceed the recommended dose. If you or someone you know has taken too much Ambien or is experiencing symptoms of an overdose, seek medical attention immediately.