Long-term use and abuse of Xanax (alprazolam) can potentially cause damage to the brain. Xanax is a central nervous system (CNS) depressant, which means it slows down activity in the brain and nervous system. Over time, the brain can adapt to the presence of Xanax and require higher doses to achieve the same effect. This can lead to physical dependence and addiction, which can cause long-term changes in the brain.
Additionally, long-term Xanax use has been associated with cognitive impairments such as memory loss, attention deficits, and problems with executive function. It is also possible for Xanax to cause brain damage in cases of overdose, which can lead to coma, seizures, or death. It is important to use Xanax only as directed by a healthcare professional and to seek medical help if you experience any concerning symptoms.