Yes, Xanax can cause or worsen symptoms of depression in some people. Xanax belongs to a class of drugs called benzodiazepines, which are commonly used to treat anxiety and panic disorders. However, they can also have side effects such as drowsiness, confusion, and depression. Xanax can also be habit-forming, and long-term use can lead to physical and psychological dependence. It’s important to talk to a doctor if you experience any negative effects while taking Xanax, including symptoms of depression.