Xanax overdose can lead to serious health complications, including respiratory depression, seizures, and coma. In some cases, Xanax overdose can result in permanent brain damage, especially if the overdose causes prolonged hypoxia (lack of oxygen to the brain). However, the likelihood of brain damage from a Xanax overdose depends on several factors, including the dose of Xanax taken, how long the overdose lasts, and the individual’s overall health status. It is important to seek medical attention immediately if you suspect a Xanax overdose or are experiencing any concerning symptoms after taking Xanax.