Clonidine is a medication that is sometimes used to help manage withdrawal symptoms during the detoxification process from opioids or alcohol. Clonidine works by reducing sympathetic nervous system activity, which can help to decrease some of the physical symptoms of withdrawal, such as anxiety, agitation, sweating, and rapid heartbeat. It can also help to reduce cravings for drugs or alcohol. While clonidine can be helpful for some people during detox, it is important to note that it is not a cure for addiction and should be used as part of a comprehensive treatment plan that includes counseling, support groups, and other evidence-based therapies.