Addiction101 Addiction Network

The Sinclair Method is a treatment for alcohol addiction that involves using the medication naltrexone and a specific protocol for taking it while continuing to drink alcohol. The method is based on the theory that alcohol addiction is caused by changes in the brain’s reward system, which can be reversed through the use of medication and continued exposure to alcohol.

Naltrexone is an opioid antagonist that blocks the brain’s natural opioids from interacting with alcohol, reducing the pleasure and reinforcing effects of alcohol consumption. The Sinclair Method involves taking naltrexone about one hour before drinking alcohol, and continuing to do so over several months while gradually reducing alcohol intake.

The theory behind the Sinclair Method is that repeated exposure to alcohol while taking naltrexone will gradually lead to a reprogramming of the brain’s reward system, reducing the craving and compulsion to drink alcohol. Over time, patients may find that they are able to reduce their alcohol intake or even abstain from alcohol altogether.

It’s worth noting that the Sinclair Method is a controversial treatment approach, with some experts questioning its effectiveness and safety. As with any treatment for addiction, it’s important to consult with a healthcare professional before starting the Sinclair Method or any other treatment approach.