Pristiq (desvenlafaxine) is an antidepressant medication that affects serotonin and norepinephrine in the brain. Withdrawal symptoms can occur when stopping or reducing the dosage of Pristiq. These symptoms can last for several weeks or even months, depending on the individual and the duration of treatment. The severity and duration of Pristiq withdrawal symptoms can vary widely from person to person. Some common withdrawal symptoms include irritability, anxiety, insomnia, dizziness, headaches, and nausea. It is important to talk to a healthcare professional before stopping Pristiq, as they can provide guidance on how to safely taper off the medication and minimize the risk of withdrawal symptoms.