The amount of clonidine needed to cause an overdose can vary depending on several factors such as the person’s age, weight, health, and tolerance to the drug. Additionally, clonidine overdose can be complicated by the use of other drugs or alcohol, which can increase the risk of serious complications.

However, as a general guideline, a clonidine overdose is considered to occur at doses of 5 mg or higher. It is important to note that even lower doses can be dangerous, especially in individuals who are not used to taking clonidine or who have medical conditions that can increase their sensitivity to the drug. If you suspect a clonidine overdose, seek medical attention immediately.