Substance abuse can negatively affect academic performance in several ways. It can cause memory problems, impair concentration, decrease motivation, and decrease attendance. Substance abuse can also lead to behavioral problems, such as increased aggression or impulsivity, that can lead to disciplinary action and academic consequences. Additionally, substance abuse can cause physical health problems that can interfere with school attendance and performance. Finally, substance abuse can lead to mental health problems, such as depression and anxiety, that can further impact academic performance.