Addiction101 Addiction Network

Currently, there are no FDA-approved medications specifically designed for treating cocaine addiction. However, some medications have shown promise in reducing cocaine use and cravings, as well as treating co-occurring mental health conditions. The following are some medications that may be used to treat cocaine addiction:

Topiramate: Topiramate is an anticonvulsant medication that can help reduce cravings and the severity of withdrawal symptoms. It has also shown some efficacy in reducing cocaine use.

Baclofen: Baclofen is a muscle relaxant medication that has shown some promise in reducing cravings and cocaine use.

Disulfiram: Disulfiram is a medication that is used to treat alcohol addiction, but it may also be helpful in treating cocaine addiction. It works by creating an unpleasant reaction when cocaine is consumed, which can discourage use.

Modafinil: Modafinil is a medication that is typically used to treat narcolepsy and other sleep disorders. It has also been shown to improve cognitive function and may be helpful in treating cocaine addiction.

Antidepressants: Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), may be used to treat co-occurring mental health conditions, such as depression and anxiety, which can contribute to cocaine addiction.

It’s important to note that these medications should only be used under the supervision of a healthcare provider and as part of a comprehensive treatment plan for cocaine addiction. Behavioral therapies, such as cognitive-behavioral therapy (CBT) and contingency management, are also essential components of treatment for cocaine addiction.