A safe injection site (SIS) is a medically supervised facility where people can use illicit drugs under the supervision of trained healthcare professionals. These facilities are designed to reduce the harms associated with drug use, including the spread of infectious diseases such as HIV and hepatitis C, and the risk of overdose. Safe injection sites typically provide sterile injecting equipment and supplies, as well as access to other harm reduction services such as counseling, drug treatment, and medical care. The primary goal of safe injection sites is to save lives and improve the health of people who use drugs.