Many substances of abuse can influence a person’s mood, including:

Stimulants: Stimulants such as cocaine, amphetamines, and methamphetamine can increase energy, alertness, and feelings of euphoria, but can also cause anxiety, irritability, and paranoia.

Depressants: Depressants such as alcohol, opioids, and benzodiazepines can cause relaxation and feelings of calm, but can also lead to depression, apathy, and decreased motivation.

Hallucinogens: Hallucinogens such as LSD, psilocybin, and PCP can cause alterations in perception, mood, and thought, but can also lead to anxiety, paranoia, and psychotic symptoms.

Marijuana: Marijuana can cause feelings of relaxation, euphoria, and altered perception, but can also lead to anxiety, paranoia, and memory impairment.

Inhalants: Inhalants such as solvents, aerosols, and gases can cause feelings of euphoria and altered perception, but can also lead to confusion, dizziness, and aggression.

Overall, the specific effects of each substance on an individual’s mood can vary depending on a range of factors, including the substance, the amount used, and the individual’s unique physiological and psychological makeup.