There is no evidence to suggest that alcohol consumption will directly stop penicillin from working. However, excessive alcohol consumption can have negative effects on the body’s ability to fight infections, which can interfere with the effectiveness of antibiotics like penicillin.

In addition, alcohol consumption can increase the risk of side effects associated with penicillin, such as nausea, vomiting, and diarrhea. Alcohol can also interact with the liver’s ability to process penicillin, which can affect the rate of metabolism and clearance of the medication from the body.

It is recommended that individuals taking penicillin avoid or limit alcohol consumption to ensure safe and effective treatment. It is important to follow the instructions provided by healthcare providers regarding medication use and to inform them of any alcohol consumption or other medications or supplements being taken to avoid any potential interactions.