Yes, stopping certain drugs can cause seizures. This is particularly true for drugs that act on the central nervous system, such as benzodiazepines, barbiturates, and alcohol. These drugs can cause physical dependence, and sudden cessation of use or a rapid decrease in dosage can trigger withdrawal symptoms, which can include seizures. Other drugs, such as certain antidepressants, antipsychotics, and stimulants, can also cause seizures if abruptly stopped or rapidly tapered off. It is important to work with a healthcare professional to properly taper off medications and avoid withdrawal symptoms and potential complications such as seizures.