Clonidine is sometimes used off-label to help manage the symptoms of benzodiazepine withdrawal, but it is not approved by the U.S. Food and Drug Administration (FDA) for this purpose. Clonidine is an alpha-2 adrenergic agonist that can help reduce anxiety, agitation, and insomnia associated with benzodiazepine withdrawal. However, its effectiveness can vary from person to person, and it may not be suitable or safe for everyone. If you are considering using clonidine to manage benzodiazepine withdrawal symptoms, it is important to talk to a healthcare provider first. They can help you determine if clonidine is appropriate for your individual situation and provide guidance on how to use it safely.