Clonidine is not typically abused in the same way as drugs of abuse like opioids or stimulants. However, like any medication, clonidine can be misused or abused. Clonidine abuse can involve taking the medication in larger doses than prescribed, taking it more frequently than recommended, or using it in a way other than prescribed, such as crushing and snorting the pills to try to achieve a faster or more intense high. Misusing or abusing clonidine can lead to serious side effects, including dangerously low blood pressure, slowed heart rate, and respiratory depression. It’s important to take clonidine only as prescribed by a doctor and to discuss any concerns or questions about the medication with a healthcare professional.