Substance abuse is a significant problem in South Africa, with high rates of drug and alcohol use reported across the country. According to a national survey conducted by the South African Community Epidemiology Network on Drug Use (SACENDU), cannabis is the most commonly used drug in South Africa, followed by alcohol, methamphetamine, and heroin.

Substance abuse has a number of negative consequences in South Africa, including increased rates of crime and violence, as well as health problems such as HIV/AIDS, tuberculosis, and other infectious diseases. Substance abuse is also a significant contributor to the country’s burden of mental health problems, with high rates of depression, anxiety, and other mental health disorders reported among individuals who abuse drugs and alcohol.

Efforts to address substance abuse in South Africa have included a range of prevention, treatment, and harm reduction initiatives. These include public education campaigns, substance abuse treatment programs, and efforts to reduce drug-related harm through initiatives such as needle exchange programs and opioid substitution therapy.

However, many challenges remain in addressing substance abuse in South Africa, including limited access to treatment and resources, high levels of poverty and unemployment, and ongoing issues related to drug trafficking and organized crime.