If Percocet (a combination of oxycodone and acetaminophen) doesn’t work, it may be due to a variety of reasons such as:

Tolerance: With prolonged use of Percocet, your body may develop a tolerance to the medication, meaning that you may require higher doses to achieve the same effect.

Drug interactions: If you are taking other medications, it’s possible that they could interact with Percocet and reduce its effectiveness.

Improper use: It’s important to follow the dosing instructions carefully and not to exceed the recommended dose.

Underlying condition: If you have an underlying medical condition that is causing your pain, Percocet may not be the best medication for you.

If you are experiencing persistent pain despite taking Percocet as prescribed, it’s important to talk to your healthcare provider. They may be able to adjust your dosage or recommend alternative treatment options.