The World Health Organization (WHO) collects and analyzes data on substance abuse and related issues from around the world. Some key statistics on substance abuse include:

Alcohol: In 2016, alcohol was responsible for 3 million deaths globally, accounting for 5.3% of all deaths. Alcohol use is also a leading risk factor for premature death and disability, with an estimated 5.1% of the global burden of disease and injury attributable to alcohol.

Illicit drug use: An estimated 269 million people aged 15-64 years used illicit drugs in 2018, representing 5.3% of the global population in that age group. The global prevalence of opioid use disorders has also increased significantly in recent years, with an estimated 27 million people worldwide affected in 2018.

Tobacco: Tobacco use is a major cause of preventable death and disease, responsible for an estimated 8 million deaths globally each year. Approximately 1.3 billion people currently use tobacco products, with smoking being the most common form of use.

Mental health: Substance abuse and mental health issues are closely linked, with substance use disorders being a common co-occurring condition among people with mental health disorders. In 2017, an estimated 792 million people globally were affected by mental health disorders, with depression being the leading cause of disability worldwide.

These statistics highlight the significant impact that substance abuse and related issues can have on individuals, families, communities, and societies as a whole. They also underscore the need for comprehensive, evidence-based approaches to prevention, treatment, and support for people affected by substance use disorders and related issues.